TIA1 抗体 (N-Term)
Quick Overview for TIA1 抗体 (N-Term) (ABIN3042843)
抗原
See all TIA1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 98-110, N-Term
-
原理
- Anti-Nucleolysin TIA-1 isoform p40 TIA1 Antibody Picoband®
-
序列
- STQRSQDHFH VFV
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-Nucleolysin TIA-1 isoform p40 TIA1 Antibody (ABIN3042843). Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human TIA1, identical to the related mouse sequence.
-
亚型
- IgG
-
-
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibody
TIA1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-215) antibodyTIA1 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A3B9 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibodyTIA1 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-193) antibodyTIA1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-215) antibodyTIA1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2A10B12 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibodyTIA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (Internal Region) antibodyVerified TIA1 适用: 人 WB, IF, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-214) antibodyTIA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (Internal Region) antibodyTIA1 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (C-Term) antibodyTIA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Mouse
1. Hackman, P., Sarparanta, J., Lehtinen, S., Vihola, A., Evila, A., Jonson, P. H., Luque, H., Kere, J., Screen, M., Chinnery, P. F., Ahlberg, G., Edstrom, L., Udd, B. Welander distal myopathy is caused by a mutation in the RNA-binding protein TIA1. Ann. Neurol. 73: 500-509, 2013. 2. Klar, J., Sobol, M., Melberg, A., Mabert, K., Ameur, A., Johansson, A. C. V., Feuk, L., Entesarian, M., Orlen, H., Casar-Borota, O., Dahl, N. Welander distal myopathy caused by an ancient founder mutation in TIA1 associated with perturbed splicing. Hum. Mutat. 34: 572-577, 2013. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
储存液
- Thimerosal (Merthiolate), Sodium azide
-
注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
-
别名
- TIA1
-
背景
-
Synonyms: Nucleolysin TIA-1 isoform p40,RNA-binding protein TIA-1,T-cell-restricted intracellular antigen-1,TIA-1,p40-TIA-1,TIA1,
Tissue Specificity: Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined.
Background: TIA1, also called WDM, encodes an RNA-binding protein involved in splicing regulation and translational repression. The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. By in situ hybridization, this gene is mapped to chromosome 2p13.3. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is though to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing.
Sequence Similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
-
分子量
- 274 kDa
-
UniProt
- P31483
抗原
-
