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UBD 抗体 (N-Term)

UBD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042826
发货至: 中国
  • 抗原 See all UBD 抗体
    UBD (Ubiquitin D (UBD))
    抗原表位
    • 10
    • 9
    • 8
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-40, N-Term
    适用
    • 44
    • 43
    • 20
    • 2
    • 2
    • 2
    • 1
    宿主
    • 56
    • 4
    克隆类型
    • 48
    • 12
    多克隆
    标记
    • 25
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBD antibody is un-conjugated
    应用范围
    • 48
    • 25
    • 24
    • 22
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Ubiquitin D(UBD) detection. Tested with WB, IHC-P in Human.
    序列
    YDSVKKIKEH VRSK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Ubiquitin D(UBD) detection. Tested with WB, IHC-P in Human.
    Gene Name: ubiquitin D
    Protein Name: Ubiquitin D
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human Diubiquitin(27-40aa YDSVKKIKEHVRSK), different from the related mouse and rat sequences by five amino acids.
    亚型
    IgG
    Top Product
    Discover our top product UBD Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    UBD (Ubiquitin D (UBD))
    别名
    UBD (UBD 产品)
    别名
    FAT10 antibody, GABBR1 antibody, UBD-3 antibody, ubiquitin D antibody, UBD antibody, Ubd antibody
    背景
    Ubiquitin D, also called UBD or FAT10 is a protein that in humans is encoded by the UBD gene. This gene is mapped to 6p22.1. Ubiquitin-like protein modifier can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome in a NUB1L-dependent manner. This gene may be involved in dendritic cell(DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. It may be involved in the formation of aggresomes when proteasome is saturated or impaired. This gene mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus(HIV)-associated nephropathy(HIVAN). It probably functions as a survival factor.

    Synonyms: Diubiquitin antibody|FAT10 antibody|UBD 3 antibody|Ubd antibody|UBD_HUMAN antibody|Ubiquitin D antibody|Ubiquitin like protein FAT10 antibody|Ubiquitin-like protein FAT10 antibody
    UniProt
    O15205
    途径
    Ubiquitin Proteasome Pathway
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