Growth Hormone 1 抗体 (AA 27-216)
Quick Overview for Growth Hormone 1 抗体 (AA 27-216) (ABIN3042811)
抗原
See all Growth Hormone 1 (GH1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-216
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原理
- Anti-Growth Hormone/GH1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Growth Hormone/GH1 Antibody (ABIN3042811). Tested in ELISA, IHC, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived rat GH recombinant protein (Position: F27-F216).
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亚型
- IgG
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anti-Growth Hormone 1 (GH1) antibody
GH1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GH-3155 unconjugated
anti-Growth Hormone 1 (GH1) (AA 28-217) antibodyGH1 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone 1 (GH1) (AA 58-187) antibodyGH1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GH-1371 unconjugated
anti-Growth Hormone 1 (GH1) (AA 1-217) antibodyGH1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3H1C2 unconjugated
anti-Growth Hormone 1 (GH1) (AA 28-216) antibodyGH1 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone 1 (GH1) (AA 1-217) antibodyGH1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G6 unconjugated
anti-Growth Hormone 1 (GH1) antibodyGH1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone 1 (GH1) (AA 28-216) antibodyGH1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone 1 (GH1) (AA 27-216) antibodyGH1 适用: 犬 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Niall, H. D., Hogan, M. L., Sauer, R., Rosenblum, I. Y., Greenwood, F. C. : Sequence of pituitary and placental lactogenic and growth hormones: evolution from a primordial peptide by gene reduplication. Proc. Nat. Acad. Sci. 68: 866-869, 1971. 2. Sundstrom, M., Lundqvist, T., Rodin, J., Giebel, L. B., Milligan, D., Norstedt, G. : Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 angstrom resolution. J. Biol. Chem. 271: 32197-32203, 1996. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Growth Hormone 1 (GH1)
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别名
- GH1
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背景
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Synonyms: Somatotropin,Growth hormone,Gh1,Gh,
Tissue Specificity: Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue. .
Background: Growth Hormone (GH) is mapped to 17q22-q24. Human growth hormone has a molecular mass of 22,005 and contains 191 amino acid residues with 2 disulfide bridges. Rat GH shares 98 % amino acid sequence homology with mouse. It binds two receptor molecules and thereby induces signal transduction through receptor dimerization. At high concentrations, GH acts as an antagonist because of a large difference in affinities at the respective binding sites.
Sequence Similarities: Belongs to the heparin-binding growth factors family.
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分子量
- 22 kDa
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UniProt
- P01244
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途径
- NF-kappaB Signaling, JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
抗原
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