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Crk 抗体 (AA 2-246)

Name: Crk 抗体 (AA 2-246)
SKU: ABIN3042758
Availability: OutOfStock

CRK 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

Observed bind size: 34KD (Crk 抗体 (AA 2-246))

Anti-Crk p38 Picoband antibody, IHC(P): Mouse Intestine Tissue (Crk 抗体 (AA 2-246))

IHC

Anti-Crk p38 Picoband antibody, IHC(P): Rat Brain Tissue (Crk 抗体 (AA 2-246))

IHC

Anti-Crk p38 Picoband antibody, All lanes: Anti Crk p38 at 0. (Crk 抗体 (AA 2-246))

Anti-Crk p38 Picoband antibody, IHC(P): Human Lung Cancer Tissue (Crk 抗体 (AA 2-246))

IHC

5 images

产品编号 ABIN3042758

发货至: 中国

Datasheet as PDF

抗原 See all Crk (CRK) 抗体

Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
抗原表位
26

14

10

6

2

1

1

1

1

1

1

1

1

1
AA 2-246
适用
78

17

13

5

2

2

1

1

1

1

1
人, 小鼠, 大鼠
宿主
68

10
兔
Compatible Secondaries
克隆类型
66

12
多克隆
标记
37

5

4

4

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This Crk antibody is un-conjugated
应用范围
55

31

25

25

14

12

9

7

7

5

4

2

2

2

2
Western Blotting (WB), Immunohistochemistry (IHC)

原理

Anti-Crk p38 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Crk p38 Antibody Picoband® (ABIN3042758). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Crk p38 recombinant protein (Position: A2-R246). Human Crk p38 shares 99% and 100% amino acid (aa) sequences identity with mouse and rat Crk p38, respectively.

亚型

IgG

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anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 1-204) antibody
CRK 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (pTyr221) antibody
CRK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 1-204) antibody
CRK 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated

anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 122-302) antibody
CRK 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (Center) antibody
CRK 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (pTyr221) antibody
CRK 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 40-196) antibody
CRK 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) antibody
CRK 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (Ser262) antibody
CRK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
1. Mayer BJ, Hanafusa H (1990). "Association of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activity.". Proc Natl Acad Sci U S A 87 (7): 2638-42. 2. Matsuki T, Pramatarova A, Howell BW (June 2008). "Reduction of Crk and CrkL expression blocks reelin-induced dendritogenesis". J. Cell. Sci. 121 (Pt 11): 1869-75. 3. Park TJ, Curran T (December 2008). "Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway". J. Neurosci. 28 (50): 13551-62.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

别名

CRK (CRK 产品)

背景

Synonyms: Adapter molecule crk,Proto-oncogene c-Crk,p38,CRK,
Tissue Specificity: Highly expressed in placenta.
Background: CRK, also known as p38 or CRKII, is a protein that in humans is encoded by the CRK gene. This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It is mapped to 17p13.3. The CRK protein participates in the Reelin signaling cascade downstream of DAB1. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Sequence Similarities: Belongs to the CRK family.

分子量

34 kDa

基因ID

1398

UniProt

P46108

途径

Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor