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Crk 抗体 (Center)

This 兔 多克隆 antibody specifically detects Crk in WB, IF 和 ICC. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN2854888
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Crk 抗体 (Center) (ABIN2854888)

抗原

See all Crk (CRK) 抗体
Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

适用

  • 107
  • 32
  • 28
  • 7
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 95
  • 12

克隆类型

  • 74
  • 33
多克隆

标记

  • 46
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This Crk antibody is un-conjugated

应用范围

  • 84
  • 35
  • 35
  • 27
  • 27
  • 24
  • 12
  • 9
  • 7
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 39
    • 15
    • 10
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    交叉反应

    交叉反应 (详细)

    Bovine (100 %)

    产品特性

    Rabbit Polyclonal antibody to CRK (v-crk sarcoma virus CT10 oncogene homolog (avian))
    CRK antibody [N2C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human CRK. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

    说明

    Positive Control: 293T , A431 , H1299 , HepG2 , Raji , NIH-3T3

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

    别名

    CRK

    背景

    This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

    分子量

    34 kDa

    基因ID

    1398

    途径

    Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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