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CREB1 抗体 (AA 1-177)

CREB1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042756
发货至: 中国
  • 抗原 See all CREB1 抗体
    CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
    抗原表位
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    AA 1-177
    适用
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    人, 大鼠
    宿主
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    克隆类型
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    多克隆
    标记
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    This CREB1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Cyclic AMP-responsive element-binding protein 1(CREB1) detection. Tested with WB in Human,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Cyclic AMP-responsive element-binding protein 1(CREB1) detection. Tested with WB in Human,Rat.
    Gene Name: cAMP responsive element binding protein 1
    Protein Name: Cyclic AMP-responsive element-binding protein 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human CREB recombinant protein (Position: M1-T177). Human CREB shares 99% and 98% amino acid (aa) sequences identity with mouse and rat CREB, respectively.
    亚型
    IgG
    Top Product
    Discover our top product CREB1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for CREB is approximately 0.25 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Qiao, Huang, Xu, Zhao, Ran, Shen: "LncRNA DQ786243 affects Treg related CREB and Foxp3 expression in Crohn's disease." in: Journal of biomedical science, Vol. 20, pp. 87, (2014) (PubMed).

  • 抗原
    CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
    别名
    CREB1 (CREB1 产品)
    别名
    creb antibody, CREB1 antibody, Creb1 antibody, CREB antibody, 2310001E10Rik antibody, 3526402H21Rik antibody, AV083133 antibody, Creb antibody, Creb-1 antibody, creb1 antibody, zgc:55598 antibody, cAMP responsive element binding protein 1 antibody, cAMP responsive element binding protein antibody, cAMP responsive element binding protein 1 S homeolog antibody, cAMP responsive element binding protein 1a antibody, CREB1 antibody, creb1 antibody, CREB antibody, Creb1 antibody, creb1.S antibody, creb1a antibody
    背景
    CREB1, also known as cAMP responsive element binding protein 1, is a protein that in humans is encoded by the CREB1 gene. It is mapped to 2q33.3. This protein binds the cAMP response element, a DNA nucleotide sequence present in many viral and cellular promoters. The binding of CREB1 stimulates transcription. This protein is a CREB transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.

    Synonyms: Active transcription factor CREB antibody|cAMP response element binding protein 1 antibody|cAMP response element binding protein antibody|cAMP responsive element binding protein 1 antibody|cAMP-responsive element-binding protein 1 antibody|CREB 1 antibody|CREB antibody|CREB-1 antibody|CREB1 antibody|CREB1_HUMAN antibody|Cyclic AMP-responsive element-binding protein 1 antibody|MGC9284 antibody|OTTHUMP00000163864 antibody|OTTHUMP00000163865 antibody|OTTHUMP00000206660 antibody|OTTHUMP00000206662 antibody|OTTHUMP00000206667 antibody|Transactivator protein antibody
    基因ID
    12912
    UniProt
    P16220
    途径
    TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
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