L-Selectin 抗体 (Middle Region)
Quick Overview for L-Selectin 抗体 (Middle Region) (ABIN3042616)
抗原
See all L-Selectin (SELL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-141, Middle Region
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原理
- Anti-CD62L/SELL Antibody Picoband®
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序列
- KEDCVEIYIK RERDSGK
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-CD62L/SELL Antibody (ABIN3042616). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of mouse L-selectin, identical to the related rat sequence.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat
1. "Entrez Gene: SELL selectin L (lymphocyte adhesion molecule 1)". 2. Cotran, Kumar, Collins (1998). Robbins Pathologic Basis of Disease. Philadelphia: W.B Saunders Company. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- L-Selectin (SELL) (Selectin L (SELL))
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别名
- SELL
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背景
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Synonyms: L-selectin,CD62 antigen-like family member L,Leukocyte adhesion molecule 1,LAM-1,Leukocyte-endothelial cell adhesion molecule 1,LECAM1,Lymph node homing receptor,Lymphocyte antigen 22,Ly-22,Lymphocyte surface MEL-14 antigen,CD62L,Sell,Lnhr, Ly-22, Ly22,
Tissue Specificity: Predominantly expressed in lymphoid tissue. .
Background: L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.
Sequence Similarities: Belongs to the selectin/LECAM family.
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分子量
- 70 kDa
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UniProt
- P18337
抗原
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