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L-Selectin 抗体 (Middle Region)

This anti-L-Selectin antibody is a 兔 多克隆 antibody detecting L-Selectin in WB. Suitable for 小鼠 和 大鼠.
产品编号 ABIN3042616
发货至: 中国

Quick Overview for L-Selectin 抗体 (Middle Region) (ABIN3042616)

抗原

See all L-Selectin (SELL) 抗体
L-Selectin (SELL) (Selectin L (SELL))

适用

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小鼠, 大鼠

宿主

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克隆类型

  • 151
  • 50
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多克隆

标记

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This L-Selectin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 125-141, Middle Region

    原理

    Anti-CD62L/SELL Antibody Picoband®

    序列

    KEDCVEIYIK RERDSGK

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-CD62L/SELL Antibody (ABIN3042616). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of mouse L-selectin, identical to the related rat sequence.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat
    1. "Entrez Gene: SELL selectin L (lymphocyte adhesion molecule 1)". 2. Cotran, Kumar, Collins (1998). Robbins Pathologic Basis of Disease. Philadelphia: W.B Saunders Company.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    L-Selectin (SELL) (Selectin L (SELL))

    别名

    SELL

    背景

    Synonyms: L-selectin,CD62 antigen-like family member L,Leukocyte adhesion molecule 1,LAM-1,Leukocyte-endothelial cell adhesion molecule 1,LECAM1,Lymph node homing receptor,Lymphocyte antigen 22,Ly-22,Lymphocyte surface MEL-14 antigen,CD62L,Sell,Lnhr, Ly-22, Ly22,

    Tissue Specificity: Predominantly expressed in lymphoid tissue. .

    Background: L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.

    Sequence Similarities: Belongs to the selectin/LECAM family.

    分子量

    70 kDa

    UniProt

    P18337
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