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PD-1 抗体 (AA 101-288)

PDCD1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042500
发货至: 中国
  • 抗原 See all PD-1 (PDCD1) 抗体
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    抗原表位
    • 16
    • 8
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    AA 101-288
    适用
    • 131
    • 74
    • 24
    • 5
    • 3
    • 1
    人, 大鼠
    宿主
    • 75
    • 60
    • 24
    • 11
    • 9
    • 3
    • 2
    克隆类型
    • 126
    • 55
    • 2
    多克隆
    标记
    • 93
    • 13
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    • 5
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    This PD-1 antibody is un-conjugated
    应用范围
    • 120
    • 57
    • 45
    • 37
    • 36
    • 19
    • 13
    • 13
    • 13
    • 12
    • 9
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    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Programmed cell death protein 1(PDCD1) detection. Tested with WB in Human,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Programmed cell death protein 1(PDCD1) detection. Tested with WB in Human,Rat.
    Gene Name: programmed cell death 1
    Protein Name: Programmed cell death protein 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human PD1 recombinant protein (Position: P101-L288). Human PD1 shares 59% amino acid (aa) sequence identity with mouse PD1.
    亚型
    IgG
    Top Product
    Discover our top product PDCD1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for PD1 is approximately 0.5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    别名
    PDCD1 (PDCD1 产品)
    别名
    CD279 antibody, PD-1 antibody, PD1 antibody, SLEB2 antibody, hPD-1 antibody, hPD-l antibody, Ly101 antibody, Pdc1 antibody, programmed cell death 1 antibody, PDCD1 antibody, Pdcd1 antibody
    背景
    PDCD1(Programmed cell death 1), also called PD1, encodes a cell surface receptor that is a member of the B7 superfamily involved in immunomodulation. This gene is mapped to 2q37.3. PDCD1 acts as an inhibitory molecule on T cells after interacting with its ligands PDL1 and PDL2. The PDCD1 gene contains 5 exons. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. Using flow cytometric analysis, It has been found that expression of PDCD1 was upregulated on CD16-positive and CD16-negative monocytes, but not on dendritic cells, in viremic HIV-positive patients, but not in highly active antiretroviral therapy (HAART)-treated HIV-positive patients. PDCD1 upregulation in monocytes was induced by microbial Toll-like receptor ligands and inflammatory cytokines.

    Synonyms: CD279 antibody|CD279 antigen antibody|hPD l antibody|hPD-1 antibody|hSLE1 antibody|PD 1 antibody|PD-1 antibody|PD1 antibody|PDCD 1 antibody|PDCD1 antibody|PDCD1_HUMAN antibody|Programmed cell death 1 antibody|Programmed cell death protein 1 antibody|Protein PD 1 antibody|Protein PD-1 antibody|SLEB2 antibody|Systemic lupus erythematosus susceptibility 2 antibody
    基因ID
    5133
    UniProt
    Q15116
    途径
    Cancer Immune Checkpoints
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