SLUG 抗体 (Middle Region)
(1 reference)Quick Overview for SLUG 抗体 (Middle Region) (ABIN3042486)
抗原
See all SLUG (SNAI2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 116-148, Middle Region
-
原理
- Anti-SLUG/SNAI2 Antibody Picoband®
-
序列
- KLSDPHAIEA EKFQCNLCNK TYSTFSGLAK HKQ
-
交叉反应 （详细）
- No cross reactivity with other proteins
-
产品特性
- Anti-SLUG/SNAI2 Antibody Picoband® (ABIN3042486). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human SLUG, identical to the related mouse and rat sequences.
-
-
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibody
SNAI2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C12 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 100-200) antibodySNAI2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4B6D5 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibodySNAI2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 98-129) antibodySNAI2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) antibodySNAI2 适用: 人 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 126-268) antibodySNAI2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 89-268) antibodySNAI2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 69-132) antibodySNAI2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (Middle Region) antibodySNAI2 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 犬, 马, 兔, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 12-124) antibodySNAI2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Rat
1. "Entrez Gene: SNAI2 snail homolog 2 (Drosophila) 2. Cohen ME, Yin M, Paznekas WA, Schertzer M, Wood S, Jabs EW (Oct 1998). "Human SLUG gene organization, expression, and chromosome map location on 8q". Genomics 51 (3): 468-71. 3. Rhim H, Savagner P, Thibaudeau G, Thiery JP, Pavan WJ (Jan 1998). "Localization of a neural crest transcription factor, Slug, to mouse chromosome 16 and human chromosome 8". Mamm Genome 8 (11): 872-3. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
-
: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).
-
: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).
-
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
-
别名
- SNAI2
-
背景
-
Synonyms: Zinc finger protein SNAI2,Neural crest transcription factor Slug,Protein snail homolog 2,SNAI2,SLUG, SLUGH,
Tissue Specificity: Expressed in most adult human tissues, including spleen, thymus, prostate, testis, ovary, small intestine, colon, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not detected in peripheral blood leukocyte. Expressed in the dermis and in all layers of the epidermis, with high levels of expression in the basal layers (at protein level). Expressed in osteoblasts (at protein level). Expressed in mesenchymal stem cells (at protein level). Expressed in breast tumor cells (at protein level). .
Background: SLUG is also known as SNAI2. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Sequence Similarities: Belongs to the snail C2H2-type zinc-finger protein family.
-
分子量
- 30 kDa
-
基因ID
- 6591
-
UniProt
- O43623
抗原
-
