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FZD1 抗体 (C-Term)

This anti-FZD1 antibody is a 兔 多克隆 antibody detecting FZD1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN3042412
发货至: 中国

Quick Overview for FZD1 抗体 (C-Term) (ABIN3042412)

抗原

See all FZD1 (Fzd1) 抗体
FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FZD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 369-400, C-Term

    原理

    Anti-Frizzled homolog 1/FZD1 Antibody Picoband®

    序列

    YIAGFLLEDR VVCNDKFAED GARTVAQG

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Frizzled homolog 1/FZD1 Antibody Picoband® (ABIN3042412). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Frizzled homolog 1, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-2 μg/mL, Human
    Western blot, 0.1-0.6 μg/mL, Human
    1. "Entrez Gene: FZD1 frizzled homolog 1 (Drosophila)". 2. Gazit A, Yaniv A, Bafico A, Pramila T, Igarashi M, Kitajewski J, Aaronson SA (Oct 1999). "Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response". Oncogene 18(44): 5959-66. 3. Sagara N, Toda G, Hirai M, Terada M, Katoh M (Nov 1998). "Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7". Biochemical and Biophysical Research Communications 252 (1): 117-22.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

    别名

    FZD1

    背景

    Synonyms: Frizzled-1,Fz-1,hFz1,FzE1,FZD1,

    Tissue Specificity: Expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney.

    Background: Frizzled-1 (Frizzled homolog 1) is a protein that in humans is encoded by the FZD1 gene. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signalingproteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.

    Sequence Similarities: Belongs to the G-protein coupled receptor Fz/Smo family.

    分子量

    71 kDa

    基因ID

    8321

    途径

    WNT signaling, Asymmetric Protein Localization
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