FZD1 抗体 (C-Term)
Quick Overview for FZD1 抗体 (C-Term) (ABIN3042412)
抗原
See all FZD1 (Fzd1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 369-400, C-Term
-
原理
- Anti-Frizzled homolog 1/FZD1 Antibody Picoband®
-
序列
- YIAGFLLEDR VVCNDKFAED GARTVAQG
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
产品特性
- Anti-Frizzled homolog 1/FZD1 Antibody Picoband® (ABIN3042412). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Frizzled homolog 1, identical to the related mouse and rat sequences.
-
亚型
- IgG
-
-
-
-
应用备注
-
Immunohistochemistry (Paraffin-embedded Section), 0.5-2 μg/mL, Human
Western blot, 0.1-0.6 μg/mL, Human
1. "Entrez Gene: FZD1 frizzled homolog 1 (Drosophila)". 2. Gazit A, Yaniv A, Bafico A, Pramila T, Igarashi M, Kitajewski J, Aaronson SA (Oct 1999). "Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response". Oncogene 18(44): 5959-66. 3. Sagara N, Toda G, Hirai M, Terada M, Katoh M (Nov 1998). "Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7". Biochemical and Biophysical Research Communications 252 (1): 117-22. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
-
别名
- FZD1
-
背景
-
Synonyms: Frizzled-1,Fz-1,hFz1,FzE1,FZD1,
Tissue Specificity: Expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney.
Background: Frizzled-1 (Frizzled homolog 1) is a protein that in humans is encoded by the FZD1 gene. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signalingproteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
Sequence Similarities: Belongs to the G-protein coupled receptor Fz/Smo family.
-
分子量
- 71 kDa
-
基因ID
- 8321
-
途径
- WNT signaling, Asymmetric Protein Localization
抗原
-