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TIMD4 抗体 (C-Term)

The 兔 多克隆 anti-TIMD4 antibody is suitable to detect TIMD4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN303296
发货至: 中国
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Quick Overview for TIMD4 抗体 (C-Term) (ABIN303296)

抗原

See all TIMD4 抗体
TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 30
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多克隆

标记

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This TIMD4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 6
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    • 2
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    • 1
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    C-Term

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography.

    免疫原

    Synthetic peptide -KLH conjugated corresponding to 15 amino acid peptide from near the carboxy terminus of Human TIM-4.
  • 应用备注

    Western Blot. Immunohistochemistry on Paraffin Sections (5 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse and Rat.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
  • 抗原

    TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

    别名

    TIMD4

    背景

    The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. Studies have shown that TIM 4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM 1, and that this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM 4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain (Kuchroo et al, 2003). The TIM 4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM 1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma (Shakhov et al 2004).Synonyms: T-cell immunoglobulin and mucin domain-containing protein 4, T-cell membrane protein 4, TIM-4, TIM4, TIMD-4

    基因ID

    91937

    NCBI登录号

    NP_001140198

    UniProt

    Q96H15

    途径

    Cancer Immune Checkpoints
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