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SPARC 抗体 (AA 284-303)

SPARC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032523
发货至: 中国
  • 抗原 See all SPARC 抗体
    SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
    抗原表位
    • 15
    • 10
    • 7
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 284-303
    适用
    • 85
    • 45
    • 40
    • 13
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 79
    • 22
    • 4
    • 2
    • 2
    克隆类型
    • 83
    • 26
    多克隆
    标记
    • 64
    • 14
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPARC antibody is un-conjugated
    应用范围
    • 93
    • 46
    • 36
    • 22
    • 13
    • 13
    • 10
    • 10
    • 10
    • 9
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids 284-303 (DEWAGCFGIKQKDIDKDLVI-human) were used as the immunogen for this SPARC antibody.
    亚型
    IgG
    Top Product
    Discover our top product SPARC Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the SPARC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the SPARC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
    别名
    SPARC (SPARC 产品)
    别名
    ON antibody, AA517111 antibody, BM-40 antibody, hm:zeh0062 antibody, SPARC antibody, sparc antibody, secreted protein acidic and cysteine rich antibody, secreted acidic cysteine rich glycoprotein antibody, secreted protein, acidic, cysteine-rich (osteonectin) antibody, secreted protein, acidic, cysteine-rich (osteonectin) L homeolog antibody, secreted protein, acidic, cysteine-rich (osteonectin) S homeolog antibody, SPARC antibody, Sparc antibody, sparc antibody, sparc.L antibody, sparc.S antibody
    背景
    Secreted protein acidic and rich in cysteine, also known as Osteonectin, is a protein that in humans is encoded by the SPARC gene. The human gene is 26.5 kb long, and contains 10 exons and 9 introns and is located on chromosome 5q31-q33. SPARC is an acidic, cysteine-rich glycoprotein consisting of a single polypeptide chain that can be broken into 4 domains: 1) an Ca++ binding domains near the glutamic acidic-rich region at the amino terminus(domain I), 2) a cysteine- rich(domain II), 3) a hydrophilic region(domain III) and 4) an EF hand motif at the carboxy terminus region(domain IV). SPARC is a glycoprotein in the bone that binds sodium. It is secreted by osteoblasts during bone formation, initiating mineralization and promoting mineral crystal formation. It also shows affinity for collagen in addition to bone mineral calcium. A correlation between SPARC over expression and ampullary cancers and chronic pancreatitis has been found.
    UniProt
    P09486
    途径
    Autophagy
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