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SPARC 抗体 (AA 101-200)

SPARC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN738141
发货至: 中国
  • 抗原 See all SPARC 抗体
    SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
    抗原表位
    • 14
    • 12
    • 12
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 90
    • 44
    • 39
    • 13
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 84
    • 22
    • 4
    • 2
    • 2
    克隆类型
    • 88
    • 26
    多克隆
    标记
    • 64
    • 15
    • 9
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPARC antibody is un-conjugated
    应用范围
    • 98
    • 48
    • 39
    • 23
    • 12
    • 12
    • 10
    • 10
    • 9
    • 9
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SPARC
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Zong, Zeng, Zou, Li, Fang, Lu, Xiao, Zhang: "Effects of Polygonatum sibiricum polysaccharide on the osteogenic differentiation of bone mesenchymal stem cells in mice." in: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6169-80, (2015) (PubMed).

    Kurtul, Eroglu, Unal, Tasdemir, Orhan, Zararsiz, Baran, Kaplan, Kontas: "Prognostic Value of SPARC Expression in Unresectable NSCLC Treated with Concurrent Chemoradiotherapy." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 15, Issue 20, pp. 8911-6, (2014) (PubMed).

    Chen, Wang, Xi, Xue, He, Zhang, Zhao: "SPARC is a key regulator of proliferation, apoptosis and invasion in human ovarian cancer." in: PLoS ONE, Vol. 7, Issue 8, pp. e42413, (2012) (PubMed).

  • 抗原
    SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
    别名
    SPARC (SPARC 产品)
    别名
    ON antibody, AA517111 antibody, BM-40 antibody, hm:zeh0062 antibody, SPARC antibody, sparc antibody, secreted protein acidic and cysteine rich antibody, secreted acidic cysteine rich glycoprotein antibody, secreted protein, acidic, cysteine-rich (osteonectin) antibody, secreted protein, acidic, cysteine-rich (osteonectin) L homeolog antibody, secreted protein, acidic, cysteine-rich (osteonectin) S homeolog antibody, SPARC antibody, Sparc antibody, sparc antibody, sparc.L antibody, sparc.S antibody
    背景

    Synonyms: ON, SPARC, Basement-membrane protein 4, BM-4, Osteonectin, Secreted protein acidic and rich in cysteine

    Background: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites, an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.

    基因ID
    6678
    UniProt
    P09486
    途径
    Autophagy
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