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Pleiotrophin 抗体 (C-Term)

This anti-Pleiotrophin antibody is a 兔 多克隆 antibody detecting Pleiotrophin in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3032264
发货至: 中国

Quick Overview for Pleiotrophin 抗体 (C-Term) (ABIN3032264)

抗原

See all Pleiotrophin (PTN) 抗体
Pleiotrophin (PTN)

适用

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人, 小鼠, 大鼠

宿主

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  • 9
  • 2
  • 2

克隆类型

  • 103
  • 11
多克隆

标记

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  • 1
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This Pleiotrophin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 19
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    • 1
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    C-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the C-terminus of human Pleiotrophin (QAESKKKKKEGKKQEKMLD) was used as the immunogen for this Pleiotrophin antibody (100% homologous in human, mouse and rat).

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Pleiotrophin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Pleiotrophin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Pleiotrophin (PTN)

    别名

    Pleiotrophin

    背景

    Pleiotrophin(PTN) also known as heparin-binding brain mitogen(HBBM) or heparin-binding growth factor 8(HBGF-8) or neurite growth-promoting factor 1(NEGF1) or heparin affinity regulatory peptide(HARP) or heparin binding growth associated molecule(HB-GAM) is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection.

    UniProt

    P21246

    途径

    RTK signaling
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