ERK1/2 抗体 (N-Term)
Quick Overview for ERK1/2 抗体 (N-Term) (ABIN3031825)
抗原
See all ERK1/2 (MAPK1/3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the N-terminus of human MAPK1/3 (ARVADPDHDHTGFL) was used as the immunogen for this MAPK1/3 antibody (100% homologous in human, mouse and rat).
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 301-358) antibody
MAPK1/3 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠, Cow, Pig, 斑马鱼, 犬, 绵羊, 猴, 鱼, 马 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pThr202), (pTyr204) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠, Cow WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pThr183), (pTyr185) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pThr185), (pThr202) antibodyMAPK1/3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (C-Term) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) antibodyMAPK1/3 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pThr183), (pTyr185) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pThr202), (pTyr204) antibodyMAPK1/3 适用: 人, 小鼠 WB, ELISA, DB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pTyr205), (pTyr222) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 小鼠 Monoclonal 4D4 unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the MAPK1/3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the MAPK1/3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
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别名
- MAPK1/3
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背景
- MAPK1(ERK2) shares high homology with MAPK3(ERK1). MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Mitogen-activated protein(MAP) kinases [also known as Erks] have been established to function as important mediators of signal transduction by growth factor receptors. ERK1/ERK2-dependent activation of endogenous ribosomal transcription, while inactivation of ERK1/ERK2 causes an equally immediate reversion to the basal transcription level. ERK1/ERK2 was found to phosphorylate the architectural transcription factor UBF at amino acids 117 and 201 within HMG boxes 1 and 2, preventing their interaction with DNA. Mutation of these sites inhibited transcription activation and abrogated the transcriptional response to ERK1/ERK2.
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UniProt
- P28482
抗原
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