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Lamin B2 抗体 (AA 580-597)

This anti-Lamin B2 antibody is a 兔 多克隆 antibody detecting Lamin B2 in WB, IHC (p) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3031588
发货至: 中国

Quick Overview for Lamin B2 抗体 (AA 580-597) (ABIN3031588)

抗原

See all Lamin B2 (LMNB2) 抗体
Lamin B2 (LMNB2)

适用

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人, 小鼠, 大鼠

宿主

  • 58
  • 19

克隆类型

  • 54
  • 23
多克隆

标记

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This Lamin B2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
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    • 1
    AA 580-597

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 580-597 (EEDLFHQQGDPRTTSRGC) were used as the immunogen for this Lamin B2 antibody (100% homologous in human, mouse and rat).

    亚型

    IgG
  • 应用备注

    Titration of the Lamin B2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    The lyophilized Lamin B2 antibody can be stored at 4°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Lamin B2 (LMNB2)

    别名

    Lamin B2

    背景

    Lamin B2, also called LMNB2, is a protein associated with laminopathies. The LMNB2 gene is mapped to the G-negative subtelomeric band p13.3 of chromosome 19 by in situ hybridization. Model organisms have been used in the study of Lamin B2 function. A conditional knockout mouse line, called Lmnb2, was generated as part of the International Knockout Mouse Consortium program-a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. A highly sensitive procedure about mapping the start site of DNA replication in a 13.7-kb region of human chromosome 19 coding for lamin B2 is developed for the identification of the origin of bidirectional DNA synthesis in single-copy replicons of mammalian cells.

    UniProt

    Q03252

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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