IRAK2 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for IRAK2 抗体 (C-Term) (ABIN3031491)
抗原
See all IRAK2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- Antigen affinity
-
免疫原
- An amino acid sequence from the C-terminus of human IRAK2 (EAKRKLMENILLYKEEK) was used as the immunogen for this IRAK2 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the IRAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the IRAK2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
-
别名
- IRAK2
-
背景
- Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene. This gene is mapped to 3p25.3. Interleukin-1 receptor-associated kinase 2 is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor(IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. It binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
-
UniProt
- O43187
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
-