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IRAK2 抗体 (C-Term)

IRAK2 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044473
发货至: 中国
  • 抗原 See all IRAK2 抗体
    IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
    抗原表位
    • 15
    • 13
    • 8
    • 8
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 600-616, C-Term
    适用
    • 76
    • 11
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 77
    • 3
    克隆类型
    • 68
    • 12
    多克隆
    标记
    • 39
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRAK2 antibody is un-conjugated
    应用范围
    • 55
    • 38
    • 18
    • 14
    • 14
    • 11
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Interleukin-1 receptor-associated kinase-like 2(IRAK2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    序列
    EAKRKLMENI LLYKEEK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Interleukin-1 receptor-associated kinase-like 2(IRAK2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Gene Name: interleukin-1 receptor-associated kinase 2
    Protein Name: Interleukin-1 receptor-associated kinase-like 2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human IRAK2(600-616aa EAKRKLMENILLYKEEK), different from the related rat sequence by one amino acid, and from the related mouse sequence by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product IRAK2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
    别名
    IRAK2 (IRAK2 产品)
    别名
    IRAK-2 antibody, 6330415L08Rik antibody, AI649099 antibody, interleukin 1 receptor associated kinase 2 antibody, interleukin-1 receptor-associated kinase 2 antibody, IRAK2 antibody, Irak2 antibody
    背景
    Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene. This gene is mapped to 3p25.3. IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor(IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. It binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

    Synonyms: IRAK-2 antibody
    UniProt
    O43187
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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