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Insulin Receptor 抗体 (AA 1353-1372)

Name: Insulin Receptor 抗体 (AA 1353-1372)
SKU: ABIN3031334
Availability: OutOfStock

INSR 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

Western blot testing of Insulin Receptor antibody and Lane 1: rat kidney; 2: PANC; 3: HeLa (Insulin Receptor 抗体 (AA 1353-1372))

Western blot testing of Insulin Receptor antibody and Lane 1: rat kidney (Insulin Receptor 抗体 (AA 1353-1372))

2 images

产品编号 ABIN3031334

发货至: 中国

Datasheet as PDF

抗原 See all Insulin Receptor (INSR) 抗体

Insulin Receptor (INSR)
抗原表位
16

15

13

12

9

8

8

7

6

6

5

5

5

4

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1353-1372
适用
168

95

80

16

14

9

8

7

6

5

4

3

2

2

1

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
165

23

3

1
兔
Compatible Secondaries
克隆类型
157

35
多克隆
标记
117

16

16

7

6

5

3

3

3

3

3

3

1

1

1

1

1

1

1
This Insulin Receptor antibody is un-conjugated
应用范围
140

82

52

28

16

16

15

15

13

13

8

5

4

4

4

2

1

1

1

1
Western Blotting (WB)

纯化方法

Antigen affinity

免疫原

Amino acids 1353-1372 (RSYEEHIPYTHMNGGKKNGR) were used as the immunogen for this Insulin Receptor antibody.

亚型

IgG

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anti-Insulin Receptor (INSR) (C-Term) antibody
INSR 适用: 人, 小鼠, 大鼠, 猴, 犬, 马, Cow, 豚鼠, Pig, 兔, 小鸡, 绵羊, Hamster, 山羊, Avian, Cat, 驴 WB 宿主: 山羊 Polyclonal unconjugated

anti-Insulin Receptor (INSR) (C-Term) antibody
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anti-Insulin Receptor (INSR) (AA 51-150) antibody
INSR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 1325-1358) antibody
INSR 适用: 小鼠 WB 宿主: 兔 Polyclonal RB50340 unconjugated

anti-Insulin Receptor (INSR) (AA 1023-1298) antibody
INSR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 27-57), (N-Term) antibody
INSR 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1421 unconjugated

应用备注

The stated application concentrations are suggested starting points. Titration of the Insulin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

限制

仅限研究用
缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

-20 °C

储存方法

After reconstitution, the Insulin Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原

Insulin Receptor (INSR)

别名

Insulin Receptor (INSR 产品)

别名

CD220 antibody, HHF5 antibody, 4932439J01Rik antibody, D630014A15Rik antibody, IR antibody, IR-A antibody, IR-B antibody, 18402 antibody, CG18402 antibody, DIHR antibody, DILR antibody, DIR antibody, DIRH antibody, DIRbeta antibody, DInR antibody, DInr antibody, Dir-a antibody, Dir-b antibody, Dmel\\CG18402 antibody, INR antibody, INS antibody, Inr antibody, Inr-alpha antibody, Inr-beta antibody, InsR antibody, dINR antibody, dIR antibody, dIRH antibody, dInR antibody, dInr antibody, dInsR antibody, dinr antibody, dir antibody, er10 antibody, inr antibody, insulin/insulin-like growth factor receptor antibody, l(3)05545 antibody, l(3)93Dj antibody, l(3)er10 antibody, lnR antibody, ir-A antibody, CTK-1 antibody, ir antibody, INSR antibody, NV14476 antibody, cd220 antibody, hhf5 antibody, insulin receptor antibody, Insulin-like receptor antibody, insulin receptor L homeolog antibody, INSR antibody, Insr antibody, InR antibody, LOC100122567 antibody, LOC100451802 antibody, insr.L antibody

背景

INSR (Insulin Receptor) is a tetramer of two alpha and two beta subunits that are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. It belongs to the large class of tyrosine kinase receptors. The insulin receptor mediates their activity by causing the addition of a phosphate group to particular tyrosines on certain proteins within a cell. The INSR gene spans more than 120 kb and has 22 exons. Functional studies of the INSR SNPs show no effect on mRNA levels or splicing in peripheral blood leukocytes or on binding of insuln to mononuclear cells.

UniProt

P06213

途径

NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity