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Insulin Receptor 抗体 (AA 1353-1372)

This 兔 多克隆 anti-Insulin Receptor antibody specifically detects Insulin Receptor in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN3031334
发货至: 中国
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Quick Overview for Insulin Receptor 抗体 (AA 1353-1372) (ABIN3031334)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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人, 小鼠, 大鼠

宿主

  • 177
  • 39
  • 6
  • 2
  • 1

克隆类型

  • 145
  • 80
多克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

  • 156
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Western Blotting (WB)
  • 抗原表位

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    AA 1353-1372

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 1353-1372 (RSYEEHIPYTHMNGGKKNGR) were used as the immunogen for this Insulin Receptor antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the Insulin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Insulin Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Insulin Receptor (INSR)

    别名

    Insulin Receptor

    背景

    INSR (Insulin Receptor) is a tetramer of two alpha and two beta subunits that are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. It belongs to the large class of tyrosine kinase receptors. The insulin receptor mediates their activity by causing the addition of a phosphate group to particular tyrosines on certain proteins within a cell. The INSR gene spans more than 120 kb and has 22 exons. Functional studies of the INSR SNPs show no effect on mRNA levels or splicing in peripheral blood leukocytes or on binding of insuln to mononuclear cells.

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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