电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Gelsolin 抗体 (AA 763-775)

This anti-Gelsolin antibody is a 兔 多克隆 antibody detecting Gelsolin in WB, ICC 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN3031036
发货至: 中国

Quick Overview for Gelsolin 抗体 (AA 763-775) (ABIN3031036)

抗原

See all Gelsolin (GSN) 抗体
Gelsolin (GSN)

适用

  • 125
  • 38
  • 32
  • 12
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 102
  • 42
  • 2

克隆类型

  • 94
  • 52
多克隆

标记

  • 94
  • 10
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Gelsolin antibody is un-conjugated

应用范围

  • 114
  • 69
  • 53
  • 52
  • 26
  • 23
  • 16
  • 15
  • 14
  • 13
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 763-775

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 763-775 (WDDDYWSVDPLDR-human) were used as the immunogen for this Gelsolin antibody (100% rat homology).

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Gelsolin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Gelsolin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Gelsolin (GSN)

    别名

    Gelsolin

    背景

    Gelsolin also known as GNS is an actin-binding protein that is a key regulator of actin filament assembly and disassembly. It is one of the most potent members of the actin-severing gelsolin/villin superfamily. The gene was assigned to human chromosome 9q33.2. Gelsolin is also known as brevin, or actin-depolymerizing factor, it is the principal intracellular and extracellular actin-severing protein. Gelsolin and Gc protein together constitute the extracellular actin-scavenger system which prevents the toxic effects of actin release into the extracellular space under circumstances of cell necrosis. It may have therapeutic potential as a mucolytic agent in CF patients. The antiapoptotic activity of Gelsolin seems to prevent a step leading to cytochrome c release from the mitochondria into the cytosol.

    UniProt

    P06396

    途径

    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
You are here:
Chat with us!