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COX1 抗体 (AA 318-599)

This anti-COX1 antibody is a 兔 多克隆 antibody detecting COX1 in WB 和 IHC (p). Suitable for 人 和 大鼠.
产品编号 ABIN3030661
发货至: 中国
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Quick Overview for COX1 抗体 (AA 318-599) (ABIN3030661)

抗原

See all COX1 抗体
COX1 (Cytochrome C Oxidase Subunit I (COX1))

适用

  • 50
  • 40
  • 28
  • 3
人, 大鼠

宿主

  • 68
  • 4
  • 2

克隆类型

  • 61
  • 13
多克隆

标记

  • 26
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This COX1 antibody is un-conjugated

应用范围

  • 51
  • 24
  • 22
  • 20
  • 18
  • 13
  • 13
  • 13
  • 9
  • 5
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 318-599

    纯化方法

    Antigen affinity

    免疫原

    Human partial recombinant protein (AA 318-599) was used as the immunogen for this COX1 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the COX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the COX1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    COX1 (Cytochrome C Oxidase Subunit I (COX1))

    别名

    COX1

    背景

    Cyclooxygenase 1(COX1), also known as Prostaglandin-endoperoxide synthase (PTGS1) or Mitochondrial cytochrome c oxidase subunit 1, is the key enzyme in prostaglandin biosynthesis. The gene is approximately 40 kb long, with 11 protein-coding exons. It is 599 amino acid residues with a calculated molecular mass of approximately 68 kD. By analysis of a human/hamster somatic hybrid DNA panel, it was demonstrated that the gene maps to chromosome 9. COX1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

    UniProt

    P23219

    途径

    Proton Transport
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