COX1 抗体 (AA 318-599)
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Quick Overview for COX1 抗体 (AA 318-599) (ABIN3030661)
抗原
See all COX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 318-599
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纯化方法
- Antigen affinity
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免疫原
- Human partial recombinant protein (AA 318-599) was used as the immunogen for this COX1 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the COX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the COX1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- COX1 (Cytochrome C Oxidase Subunit I (COX1))
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别名
- COX1
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背景
- Cyclooxygenase 1(COX1), also known as Prostaglandin-endoperoxide synthase (PTGS1) or Mitochondrial cytochrome c oxidase subunit 1, is the key enzyme in prostaglandin biosynthesis. The gene is approximately 40 kb long, with 11 protein-coding exons. It is 599 amino acid residues with a calculated molecular mass of approximately 68 kD. By analysis of a human/hamster somatic hybrid DNA panel, it was demonstrated that the gene maps to chromosome 9. COX1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.
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UniProt
- P23219
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途径
- Proton Transport
抗原
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