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CDK2 抗体 (AA 277-298)

This anti-CDK2 antibody is a 兔 多克隆 antibody detecting CDK2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3030607
发货至: 中国

Quick Overview for CDK2 抗体 (AA 277-298) (ABIN3030607)

抗原

See all CDK2 抗体
CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CDK2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 277-298

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 277-298 (AKAALAHPFFQDVTKPVPHLRL) were used as the immunogen for this Cdk2 antibody (100% homologous in human, mouse and rat).

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Cdk2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Cdk2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

    别名

    Cdk2

    背景

    Cyclin-Dependent Kinase 2 is also know as p33. The protein is highly homologous to p34 (CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that< a href=../search_result.php?search_txt=cdk2>Cdk2is the human homolog of Eg1. The gene is mapped to 12q13, the same region to which the< a href=../search_result.php?search_txt=cdk4>Cdk4gene maps. Human Cyclin A binds independently to two kinases, p34/Cdc2) or p33/Cdk2. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/Cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65 % sequence identity with p34(cdc2). Cdk2 plays a unique role in cell cycle regulation of vertebrate cells.

    UniProt

    P24941

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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