CDK2 抗体 (AA 277-298)
Our Local Distributor
北京 101111
Quick Overview for CDK2 抗体 (AA 277-298) (ABIN3030607)
抗原
See all CDK2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 277-298
-
纯化方法
- Antigen affinity
-
免疫原
- Amino acids 277-298 (AKAALAHPFFQDVTKPVPHLRL) were used as the immunogen for this Cdk2 antibody (100% homologous in human, mouse and rat).
-
亚型
- IgG
-
-
-
-
应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Cdk2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the Cdk2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
-
别名
- Cdk2
-
背景
- Cyclin-Dependent Kinase 2 is also know as p33. The protein is highly homologous to p34 (CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that< a href=../search_result.php?search_txt=cdk2>Cdk2is the human homolog of Eg1. The gene is mapped to 12q13, the same region to which the< a href=../search_result.php?search_txt=cdk4>Cdk4gene maps. Human Cyclin A binds independently to two kinases, p34/Cdc2) or p33/Cdk2. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/Cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65 % sequence identity with p34(cdc2). Cdk2 plays a unique role in cell cycle regulation of vertebrate cells.
-
UniProt
- P24941
-
途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
-