Cyclin D3 抗体 (AA 136-292)
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Quick Overview for Cyclin D3 抗体 (AA 136-292) (ABIN3030597)
抗原
See all Cyclin D3 (CCND3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 136-292
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纯化方法
- Antigen affinity
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免疫原
- Human partial recombinant protein (AA 136-292) was used as the immunogen for this Cyclin D3 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Cyclin D3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Cyclin D3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Cyclin D3 (CCND3)
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别名
- Cyclin D3
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背景
- Cyclin D3 is a protein that in humans is encoded by the CCND3 gene. It is mapped to 6p21.1. The protein encoded by this gene belongs to a family of proteins whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D3 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. In addition, overexpression of CCND3 upregulated the translational activity in HeLa cells in a dose-dependent manner.
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基因ID
- 896
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
抗原
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