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CD44 抗体 (C-Term)

Name: CD44 抗体 (C-Term)
SKU: ABIN3030402
Availability: OutOfStock

This anti-CD44 antibody is a 兔多克隆 antibody detecting CD44 in WB, IHC (p), IHC (fro) 和 ICC. Suitable for 人, 小鼠和大鼠.

Western blot testing of CD44 antibody and Lane 1: rat testis; 2: rat ovary; 3: HeLa; 4: HEPA; Predicted size: 82KD; Observed size: 82KD (CD44 抗体 (C-Term))

ICC testing of HCT116 cell (CD44 抗体 (C-Term))

ICC

IHC-F testing of rat intestine tissue (CD44 抗体 (C-Term))

IHC

IHC-P: CD44 antibody testing of human intestinal cancer tissue (CD44 抗体 (C-Term))

IHC

4 images

产品编号 ABIN3030402

发货至: 中国

Quick Overview for CD44 抗体 (C-Term) (ABIN3030402)

抗原

See all CD44 抗体

CD44

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CD44 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Discover our top product CD44 Primary Antibody

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C-Term

纯化方法

Antigen affinity purified

免疫原

An amino acid sequence from the C-terminus of human CD44 (DETRNLQNVDMKIGV) was used as the immunogen for this CD44 antibody.

亚型

IgG
anti-CD44 (CD44) antibody
CD44 适用: 人, 小鼠 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8E2F3 unconjugated

anti-CD44 (CD44) antibody
KO Validated CD44 适用: 人 WB, IF, IHC (p), IP, IHC (fro), ICC, LCI 宿主: 兔 Polyclonal unconjugated

anti-CD44 (CD44) (AA 21-220) antibody
CD44 适用: 人 FACS, WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 6G2D2 unconjugated

anti-CD44 (CD44) antibody
CD44 适用: 人 FACS, WB, IHC, ELISA, IHC (p), IP, Inhibition 宿主: 小鼠 Monoclonal MEM-85 unconjugated

anti-CD44 (CD44) antibody
CD44 适用: 人, 犬, Pig FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal MEM-263 unconjugated

anti-CD44 (CD44) (AA 148-247) antibody
CD44 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD44 (CD44) (AA 36-194) antibody
CD44 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7F4F1 unconjugated

anti-CD44 (CD44) (AA 21-259) antibody
CD44 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, ELISA, IF, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

anti-CD44 (CD44) (AA 1-361) antibody
CD44 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

anti-CD44 (CD44) antibody
CD44 适用: 人, Baboon, Green Monkey FACS, WB, IHC, IF, Func, StM 宿主: 小鼠 Monoclonal 156-3C11 unconjugated

应用备注

The stated application concentrations are suggested starting amounts. Titration of the CD44 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

限制

仅限研究用
缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

-20 °C

储存方法

After reconstitution, the CD44 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
抗原

CD44

别名

CD44

背景

The CD44 gene, which is a transmembrane protein, is expressed as a family of molecular isoforms generated from alternative RNA splicing and posttranslational modifications. The gene, which contains 19 exons spanning some 50 kb of genomic DNA, is a widely expressed integral membrane protein that acts as a receptor for hyaluronan(HA) and is important to cell-extracellular matrix interaction. CD44 binding with HA can play an important role in cellular aggregation and tumor cell growth. CD44 is necessary for limb development and functions in a novel growth factor presentation mechanism. A specific CD44 splice variant is crucial for the proliferation of these mesenchymal cells. CD44 glycoproteins are involved in leukocyte extravasation but also in the regulation of growth factor activation, stability, and signaling. Moreover, it plays a pivotal role in arteriogenesis.

UniProt

P16070

途径

Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling