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CEBPB 抗体 (AA 1-200)

This anti-CEBPB antibody is a 兔 多克隆 antibody detecting CEBPB in WB, IHC (p) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3030344
发货至: 中国

Quick Overview for CEBPB 抗体 (AA 1-200) (ABIN3030344)

抗原

See all CEBPB 抗体
CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

适用

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人, 小鼠, 大鼠

宿主

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  • 16
  • 1
  • 1

克隆类型

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多克隆

标记

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This CEBPB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 1-200

    纯化方法

    Antigen affinity

    免疫原

    Human partial recombinant protein (AA 1-200) was used as the immunogen for this C/EBP beta antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the C/EBP beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the C/EBP beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

    别名

    C/EBP beta

    背景

    CCAAT/enhancer-binding protein beta, also known as is C/EBP beta, is a protein that in humans is encoded by the CEBPB gene. The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the< a href=../search_result.php?search_txt=il-6>IL-6gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. C/EBP beta is critical for normal macrophage functioning, an important immune cell sub-type. Observational work has shown that expression of C/EBP beta in blood leukocytes is positively associated with muscle strength in humans, emphasizing the importance of the immune system, and particularly macrophages, in the maintenance of muscle function.

    基因ID

    1051

    途径

    Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation
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