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Caspase 10 抗体 (AA 220-236)

CASP10 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3030289
发货至: 中国
  • 抗原 See all Caspase 10 (CASP10) 抗体
    Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
    抗原表位
    • 16
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 220-236
    适用
    • 70
    • 16
    • 6
    宿主
    • 61
    • 5
    • 2
    • 1
    • 1
    克隆类型
    • 55
    • 15
    多克隆
    标记
    • 38
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Caspase 10 antibody is un-conjugated
    应用范围
    • 36
    • 19
    • 18
    • 13
    • 13
    • 12
    • 10
    • 10
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids 220-236 (VKTFLEALPRAAVYRMN-human) were used as the immunogen for this Caspase-10 antibody. This sequence is from the large subunit
    亚型
    IgG
    Top Product
    Discover our top product CASP10 Primary Antibody
  • 应用备注
    The stated application concentrations are suggested starting points. Titration of the Caspase-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Caspase-10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
    别名
    Caspase-10 (CASP10 产品)
    别名
    xCaspase-10 antibody, alps2 antibody, caspace-10 antibody, caspase-10 antibody, flice2 antibody, mch4 antibody, xCaspace-10 antibody, ALPS2 antibody, FLICE2 antibody, MCH4 antibody, caspase 10 S homeolog antibody, caspase 10 antibody, caspase-10 antibody, casp10.S antibody, casp10 antibody, CASP10 antibody, Casp10 antibody, LOC100848685 antibody
    背景
    Caspase-10 is an enzyme that in humans is encoded by the CASP10 gene. The CASP10 gene contains 11 exons and spans about 48 kb. This gene is mapped to 2q33.1. It is transcribed in the centromere-to-telomere direction. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates CASP3 and 7, and the protein itself is processed by CASP8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this protein.
    UniProt
    Q92851
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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