BDNF 抗体 (AA 129-247)
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Quick Overview for BDNF 抗体 (AA 129-247) (ABIN3030195)
抗原
See all BDNF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 129-247
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纯化方法
- Antigen affinity
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免疫原
- Human partial recombinant protein (AA 129-247) was used as the immunogen for this BDNF antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting points. Titration of the BDNF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the BDNF antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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别名
- BDNF
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背景
- Brain-derived neurotrophic factor is a secreted protein that, in humans, is encoded by the BDNF gene. It is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor. BDNF is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is expressed within peripheral ganglia and is not restricted to neuronal target fields. It has been purified and shown to reduce the amount of naturally occurring neuronal cell death in portions of the peripheral nervous system.
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基因ID
- 12064
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UniProt
- P23560
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途径
- RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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