BID 抗体 (C-Term)
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Quick Overview for BID 抗体 (C-Term) (ABIN3030162)
抗原
See all BID 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the C-terminus of mouse Bid (NQNLFSYVRNLVRNEMD) was used as the immunogen for this Bid antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Bid antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Bid antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- BID (BH3 Interacting Domain Death Agonist (BID))
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别名
- Bid
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背景
- Bid (BH3-Interacting Domain Death Agonist), is a pro-apoptotic member of the Bcl-2 protein family. The BCL2 family of proteins consists of both antagonists and agonists that regulate apoptosis and compete through dimerization. By fluorescence in situ hybridization, Wang et al.(1998) mapped the human BID gene to 22q11. Luo et al.(1998) reported the purification of a cytosolic protein that induces cytochrome c release from mitochondria in response to caspase-8, the apical caspase activated by cell surface death receptors such as FAS and TNF.
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UniProt
- P70444
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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