beta Arrestin 1 抗体 (N-Term)
Quick Overview for beta Arrestin 1 抗体 (N-Term) (ABIN3030023)
抗原
See all beta Arrestin 1 (ARRB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the N-terminus of human ARRB1 (ANVQSFPPAPEDKKPLTRLQER) was used as the immunogen for this beta Arrestin 1 antibody (100% homologous in human, mouse and rat).
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亚型
- IgG
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anti-Arrestin, beta 1 (ARRB1) (AA 3-246) antibody
ARRB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 169-418) antibodyARRB1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IP, ICC, FACS 宿主: 兔 Monoclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 336-363), (C-Term) antibodyARRB1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB31615 unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 1-260) antibodyARRB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 369-418) antibodyARRB1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 343-371), (C-Term) antibodyARRB1 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (Ser157) antibodyARRB1 适用: 人, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the beta Arrestin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the beta Arrestin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
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别名
- beta Arrestin 1
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背景
- Beta Arrestin 1 is a protein which in humans is encoded by the ARRB1 gene. Members of arrestin/beta-arrestin protein family are though to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. By fluorescence in situ hybridization,this gene is mapped to 11q13.4. Beta Arrestin 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.
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UniProt
- P49407
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途径
- Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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