Angiopoietin 2 抗体 (AA 454-468)
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Quick Overview for Angiopoietin 2 抗体 (AA 454-468) (ABIN3029949)
抗原
See all Angiopoietin 2 (ANGPT2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 454-468
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 454-468 (NLNGMYYPQRQNTNK-human) were used as the immunogen for this Angiopoietin 2 antibody.
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亚型
- IgG
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anti-Angiopoietin 2 (ANGPT2) (AA 24-165) antibody
ANGPT2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-147) antibodyANGPT2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) antibodyANGPT2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 404-432), (C-Term) antibodyANGPT2 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB17789 unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 401-496) antibodyANGPT2 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-483) antibodyANGPT2 适用: 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-485) antibodyANGPT2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (N-Term) antibodyANGPT2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (N-Term) antibodyANGPT2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-348) antibodyANGPT2 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Angiopoietin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Angiopoietin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Angiopoietin 2 (ANGPT2)
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别名
- Angiopoietin 2
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背景
- Angiopoietin 2 and -1 are involved in the development of the endothelium by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60 % homologous with -1. It is a naturally occurring antagonist of ANGPT1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. ANGPT1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.
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UniProt
- O15123
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途径
- RTK signaling
抗原
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