SOCS1 抗体 (C-Term)
Quick Overview for SOCS1 抗体 (C-Term) (ABIN3029041)
抗原
See all SOCS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the C-terminus of human SOCS1 (NPVLRDYLSSFPFQI) was used as the immunogen for this SOCS1 antibody (100% homologous in human, mouse and rat).
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亚型
- IgG
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anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibody
SOCS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibodyVerified SOCS1 适用: 人, 小鼠 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibodySOCS1 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 35-66) antibodySOCS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibodySOCS1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 35-66), (N-Term) antibodySOCS1 适用: 小鼠, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB17347 unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 121-211) antibodySOCS1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) antibodySOCS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibodySOCS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibodySOCS1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the SOCS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the SOCS1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
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别名
- SOCS1
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背景
- Suppressor of cytokine signaling 1(SOCS1), also known as Jak-binding protein(JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.
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UniProt
- O15524
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途径
- JAK/STAT Signaling, Interferon-gamma Pathway, TLR signaling, Response to Growth Hormone Stimulus
抗原
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