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XBP1 抗体 (C-Term)

This anti-XBP1 antibody is a 兔 多克隆 antibody detecting XBP1 in WB, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN302900
发货至: 中国

Quick Overview for XBP1 抗体 (C-Term) (ABIN302900)

抗原

See all XBP1 抗体
XBP1 (X-Box Binding Protein 1 (XBP1))

适用

  • 72
  • 38
  • 11
  • 6
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 69
  • 14
  • 1

克隆类型

  • 68
  • 16
多克隆

标记

  • 50
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This XBP1 antibody is un-conjugated

应用范围

  • 70
  • 36
  • 25
  • 22
  • 13
  • 13
  • 13
  • 13
  • 10
  • 8
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 10
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody reacts to a 17 amino acid peptide from near the carboxy terminus of XBP-1.

    纯化方法

    Immunoaffinity Chromatography.

    免疫原

    Synthetic peptide corresponding to a 17 amino acid peptide from near the Carboxy terminus of XBP-1.
  • 应用备注

    Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western Blot: 1-2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline, containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at-20 °C for longer.
  • 抗原

    XBP1 (X-Box Binding Protein 1 (XBP1))

    别名

    XBP1 / TREB5

    背景

    This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. The protein contains two domains commonly found in transcription factors that confer DNA binding and dimerization capability. This gene product was also separately identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. There is also a recent finding that the same agents that cause an ER stress response, the unfolded protein response, also increase transcription of this gene. This increase in transcription requires an ER stress response consensus binding element in the promoter.Synonyms: Tax-responsive element-binding protein 5, X-box-binding protein 1, XBP-1, XBP2

    基因ID

    7494

    NCBI登录号

    NP_001073007

    UniProt

    P17861

    途径

    ER-Nucleus Signaling, Unfolded Protein Response
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