IRAK3 抗体
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北京 101111
Quick Overview for IRAK3 抗体 (ABIN302829)
抗原
See all IRAK3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to a peptide corresponding to amino acids from the carboxy terminus of IRAK-M.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide
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应用备注
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Western Blot: 0,5 - 1 μg/mL. Immunohistochemistry: 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline, containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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别名
- IRAK3
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背景
- IRAK-M, an IRAK type protein kinase, is a signal transducer for the immune response Toll-like receptor and interleukin-1 (IL-1) receptor signaling cascades. IRAK-M is immediately downstream of the MyD88 adapter protein and immediately upstream of TRAF6. At least three mRNA transcripts have been reported - an approximately 8-kb doublet and a 2.5-kb transcript that matched isolated cDNA. IRAK-M (-/-) mice have increased inflammatory responses to bacterial infection.Synonyms: IL-1 receptor-associated kinase M, IRAK-3, IRAK-M, Interleukin-1 receptor-associated kinase 3
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基因ID
- 11213
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NCBI登录号
- NP_001135995
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UniProt
- Q9Y616
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途径
- TLR signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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