PPARG 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for PPARG 抗体 (N-Term) (ABIN302768)
抗原
See all PPARG 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody is specific to PPAR gamma.
-
交叉反应 （详细）
-
Species reactivity (expected):Mouse, Pig and Canine (Dog).
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography
-
免疫原
- Synthetic peptide corresponding to a region near the amino terminus of PPAR gamma 2. Epitope: N-terminus
-
-
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 315-420) antibody
PPARG 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 101-200) antibodyPPARG 适用: 人, 小鼠, 大鼠, Cow, 绵羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibodyPPARG 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 149-273) antibodyPPARG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibodyPPARG 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer273) antibodyPPARG 适用: 人, 小鼠, 大鼠, 绵羊, 豚鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) antibodyPPARG 适用: 人 WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 8D1H8F4 unconjugated
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) antibodyPPARG 适用: 小鼠, 大鼠 IHC 宿主: 小鼠 Monoclonal 6D7B9 unconjugated
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 349-488) antibodyPPARG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 157-274) antibodyPPARG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/3200-1/10000. Western Blot: 1/1000-1/3000. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
-
别名
- PPAR-gamma
-
背景
- Since their discovery in the early 1990's, the peroxisome proliferator activated receptors (PPARs) have attracted significant attention. This is primarily because PPARs serve as receptors for two very important classes of drugs: the hypolipidemic fibrates and the insulin sensitizing thiazolidinediones. Peroxisome proliferators are non-genotoxic carcinogens that are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed PPARs. Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Upon binding fatty acids or hypolipidemic drugs, PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate the expression of target genes. There are 3 known subtypes of PPARs: PPAR-alpha, PPAR-delta and PPAR-gamma. The target genes of PPAR-alpha and PPAR-delta are primarily involved in the catabolism of fatty acids. Conversely, PPAR-gamma is activated by peroxisome proliferators such as prostaglandins, leukotrienes and anti-diabetic thiazolidinediones and affects the expression of genes involved in the storage of fatty acids. PPAR-gamma may also be involved in adipocyte differentiation. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase and cytochrome P450 through interaction with specific response elements.Synonyms: NR1C3, PPARG, Peroxisome proliferator-activated receptor gamma
-
基因ID
- 5468
-
NCBI登录号
- NP_005028
-
UniProt
- P37231
-
途径
- MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
-
