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SARM1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects SARM1 in WB, IF 和 IHC (p). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN302767
发货至: 中国
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Quick Overview for SARM1 抗体 (C-Term) (ABIN302767)

抗原

See all SARM1 抗体
SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

适用

  • 36
  • 24
  • 18
  • 1
人, 小鼠

宿主

  • 28
  • 10

克隆类型

  • 28
  • 10
多克隆

标记

  • 20
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SARM1 antibody is un-conjugated

应用范围

  • 30
  • 13
  • 11
  • 11
  • 7
  • 6
  • 6
  • 4
  • 2
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody is specific to a peptide corresponding to amino acids near the C-terminus of SARM.

    交叉反应 (详细)

    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.

    纯化方法

    Ion Exchange Chromatography

    免疫原

    Synthetic peptide corresponding to amino acids near the C-terminus of Human SARM
  • 应用备注

    Western Blot: 0,5 - 2 μg/mL. Immunohistochemistry: 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.
  • 抗原

    SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

    别名

    SARM1

    背景

    Toll-like receptors (TLRs) play an essential role in the detection and elimination of invading microbes. They are type-1 transmembrane receptors, containing extracellular leucine rich repeats and an intracellular Toll/interleukin-1 receptor (TIR) domain. Upon stimulation, these receptors interact with specific TIR domain-containing adaptor proteins. Five such adaptors have been discovered to date, MyD88, Mal (MyD88 adaptor-like)/TIRAP (TIR domain-containing adaptor protein), Trif (TIR-domain-containing adaptor inducing interferon-beta), TRAM (Trif-related adaptor molecule) and SARM (SAM and ARM-containing protein). Different TLRs use different combinations of these adaptors, leading to the activation of common and unique pathways involved in the elimination of the invading microbe.Synonyms: KIAA0524, SAM domain-containing protein 2, SAMD2, SARM, Sterile alpha and Armadillo repeat protein, Sterile alpha and TIR motif-containing protein 1, Sterile alpha motif domain-containing protein 2

    基因ID

    23098

    NCBI登录号

    NP_055892

    UniProt

    Q6SZW1

    途径

    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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