Cytokeratin 18 抗体
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北京 101111
Quick Overview for Cytokeratin 18 抗体 (ABIN3026960)
抗原
See all Cytokeratin 18 (KRT18) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Cytokeratin 18 Antibody (azide and preservative free)
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无交叉反应
- 大鼠
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产品特性
- This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
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纯化方法
- Protein G affinity chromatography
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免疫原
- A cytoskeletal preparation from A431 cells was used as the immunogen for the Cytokeratin 18 antibody.
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亚型
- IgG1, kappa
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anti-Keratin 18 (KRT18) (AA 53-150) antibody
KRT18 适用: 人, 大鼠, 小鼠, Pig WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 18 (KRT18) antibodyKRT18 适用: 哺乳动物 WB, ELISA, IHC (p), ICC, IP, ICFC 宿主: 小鼠 Monoclonal C-04 unconjugated
anti-Keratin 18 (KRT18) antibodyKRT18 适用: 人 WB, ELISA, IHC (p), ICC, IP, ICFC 宿主: 小鼠 Monoclonal DC-10 unconjugated
anti-Keratin 18 (KRT18) (AA 1-423) antibodyKRT18 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 238-396) antibodyKRT18 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 238-396) antibodyKRT18 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal E4 unconjugated
anti-Keratin 18 (KRT18) (AA 72-380) antibodyKRT18 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 1-430) antibodyKRT18 适用: 人 WB, IF, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-Keratin 18 (KRT18) (AA 69-372) antibodyKRT18 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5E8 unconjugated
anti-Keratin 18 (KRT18) (AA 69-372) antibodyKRT18 适用: 人, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
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应用备注
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Optimal dilution of the Cytokeratin 18 antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Cytokeratin 18 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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别名
- Cytokeratin 18
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背景
- This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
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UniProt
- P05783
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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