电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

MUC5AC 抗体

MUC5AC 适用: 人, 小鼠, 大鼠, 猴, Cat, 兔, 小鸡, Pig, Hedgehog IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 45M1 unconjugated
产品编号 ABIN3026776
发货至: 中国
  • 抗原 See all MUC5AC 抗体
    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
    适用
    • 88
    • 53
    • 38
    • 18
    • 17
    • 16
    • 14
    • 13
    • 12
    • 6
    • 1
    • 1
    人, 小鼠, 大鼠, 猴, Cat, 兔, 小鸡, Pig, Hedgehog
    宿主
    • 58
    • 57
    • 1
    小鼠
    克隆类型
    • 59
    • 57
    单克隆
    标记
    • 60
    • 16
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MUC5AC antibody is un-conjugated
    应用范围
    • 54
    • 41
    • 31
    • 29
    • 28
    • 19
    • 18
    • 17
    • 15
    • 13
    • 13
    • 12
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    无交叉反应
    产品特性
    This antibody recognizes the peptide core of gastric mucin M1 (>1,000 kDa), now identified as Mucin-5AC or MUC5AC. The MUC5AC epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. MUC5AC antibody reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
    纯化方法
    Protein G affinity chromatography
    免疫原
    M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient was used as the immunogen for this MUC5AC antibody.
    克隆位点
    45M1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MUC5AC Primary Antibody
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the MUC5AC antibody to be titered up or down for optimal performance.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2)

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    Store the MUC5AC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
    别名
    MUC5AC Mucin-5AC (MUC5AC 产品)
    别名
    MUC5 antibody, TBM antibody, leB antibody, 2210005L13Rik antibody, MGM antibody, mucin 5AC, oligomeric mucus/gel-forming antibody, putative gastric mucin antibody, mucin 5, subtypes A and C, tracheobronchial/gastric antibody, mucin 2, oligomeric mucus/gel-forming antibody, MUC5AC antibody, Smp_144070 antibody, Muc5ac antibody, MUC2 antibody
    背景
    This antibody recognizes the peptide core of gastric mucin M1 (>1,000  kDa), now identified as Mucin-5AC or MUC5AC. The MUC5AC epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. MUC5AC antibody reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
    基因ID
    4586
You are here:
客服