CEA 抗体 (full length, pan)
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北京 101111
Quick Overview for CEA 抗体 (full length, pan) (ABIN3026751)
抗原
See all CEA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length, pan
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原理
- Pan-CEA Antibody Cocktail / CEACAM5
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产品特性
- This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This mAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant full-length human protein was used as the immunogen for the pan-CEA antibody cocktail.
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亚型
- IgG
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anti-Carcinoembryonic Antigen Gene Family (CEA) (AA 448-572) antibody
CEA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) antibodyCEA 适用: 人 WB, IHC (p), ELISA, IF (p) 宿主: 小鼠 Monoclonal B5 unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) (AA 315-365) antibodyCEA 适用: 人 WB, IHC (p), ELISA, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) antibodyCEA 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) antibodyCEA 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 3G12 unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) (AA 400-429) antibodyCEA 适用: 人 IHC, WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) antibodyCEA 适用: 人 IHC (p), ELISA, IF (p), IF (cc) 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) (full length) antibodyCEA 适用: 人 IHC 宿主: 兔 Monoclonal 465R unconjugated Recombinant Antibody
anti-Carcinoembryonic Antigen Gene Family (CEA) (AA 400-429) antibodyCEA 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19418 unconjugated
anti-Carcinoembryonic Antigen Gene Family (CEA) antibodyCEA 适用: 人 IHC, Lbl 宿主: 小鼠 Monoclonal A5B7 unconjugated Recombinant Antibody
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应用备注
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Optimal dilution of the pan CEA antibody to be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the pan-CEA antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CEA (Carcinoembryonic Antigen Gene Family (CEA))
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别名
- CEA
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背景
- This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This mAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
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UniProt
- P06731
抗原
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