Cyclin A 抗体 (full length)
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北京 101111
Quick Overview for Cyclin A 抗体 (full length) (ABIN3026638)
抗原
See all Cyclin A (CCNA2) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 144-148, full length
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原理
- Cyclin A2 Antibody (azide and preservative free)
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产品特性
- This antibody recognizes a protein of 50-55 kDa, which is identified as Cyclin A. Its epitope is located amino acids 144-148 of the human protein. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, Cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while Cyclin B is a critical regulator of mitosis. Mutation or disruption of normal Cyclin A expression causes cells to arrest in G2-phase.
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纯化方法
- Protein G affinity chromatography
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免疫原
- Full length bovine protein was used as the immunogen for this CCNA2 antibody. The epitope has been localized to amino acids 144-148 of the human protein.
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亚型
- IgG2a, kappa
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anti-Cyclin A2 (CCNA2) antibody
KO Validated CCNA2 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 105-233) antibodyCCNA2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6B4D11 unconjugated
anti-Cyclin A2 (CCNA2) antibodyKD Validated CCNA2 适用: 人 WB, FACS, ICC, IF (p) 宿主: 兔 Monoclonal 23GB1875 unconjugated Recombinant Antibody
anti-Cyclin A2 (CCNA2) (AA 10-168) antibodyCCNA2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 190-270) antibodyCCNA2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 51-84), (N-Term) antibodyCCNA2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14617 unconjugated
anti-Cyclin A2 (CCNA2) (AA 51-84) antibodyCCNA2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 375-431) antibodyCCNA2 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) antibodyCCNA2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (C-Term) antibodyCCNA2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Monoclonal BLR369N unconjugated Recombinant Antibody
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应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Cyclin A2 antibody to be titered up or down for optimal performance.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Cyclin A2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
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别名
- Cyclin A2
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背景
- This antibody recognizes a protein of 50-55 kDa, which is identified as Cyclin A. Its epitope is located amino acids 144-148 of the human protein. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, Cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while Cyclin B is a critical regulator of mitosis. Mutation or disruption of normal Cyclin A expression causes cells to arrest in G2-phase.
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途径
- PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
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