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Insulin Receptor 抗体 (Chain beta, Internal Region)

This anti-Insulin Receptor antibody is a 兔 多克隆 antibody detecting Insulin Receptor in IHC (p). Suitable for 人.
产品编号 ABIN302612
发货至: 中国

Quick Overview for Insulin Receptor 抗体 (Chain beta, Internal Region) (ABIN302612)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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宿主

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克隆类型

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多克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Chain beta, Internal Region

    特异性

    This antibody detects Insulin Receptor (INSR) at internal domain.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    INSR antibody was raised against synthetic peptide from internal domain of human INSR / Insulin Receptor.
  • 应用备注

    Immunohistochemistry on paraffin section (10 μg/mL)Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undlited at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
  • 抗原

    Insulin Receptor (INSR)

    别名

    CD220 / INSR

    背景

    INSR is an insulin receptor type protein kinase. Binding of insulin to INSR stimulates glucose uptake. Two insulin receptor mRNA transcripts resulting from alternative splicing of exon 11 in the receptor gene are expressed in a highly regulated tissue-specific fashion. Mutations in the INSR gene contribute to diseases, including of various forms of insulin resistance, insulin-resistant diabetes mellitus, noninsulin-dependent diabetes mellitus (NIDDM), Rabson-Mendenhall syndrome and Leprechaunism (Donohue Syndrome).Synonyms: Insulin Receptor

    基因ID

    3643

    NCBI登录号

    NP_000199

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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