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CD46 抗体

This anti-CD46 antibody is a 小鼠 单克隆 antibody detecting CD46 in FACS 和 IF. Suitable for 人 和 Baboon.
产品编号 ABIN3025892
发货至: 中国

Quick Overview for CD46 抗体 (ABIN3025892)

抗原

See all CD46 抗体
CD46

适用

  • 130
  • 37
  • 23
  • 10
  • 10
  • 3
人, Baboon

宿主

  • 91
  • 62
  • 2
  • 1
小鼠

克隆类型

  • 78
  • 78
单克隆

标记

  • 63
  • 17
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  • 10
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD46 antibody is un-conjugated

应用范围

  • 93
  • 86
  • 42
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  • 39
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  • 22
  • 14
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  • 9
  • 8
  • 5
  • 5
  • 2
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  • 1
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  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

169-1-E4-3
  • 无交叉反应

    纯化方法

    Protein G affinity chromatography

    免疫原

    Stimulated human leukocytes were used as the immunogen for the CD46 antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal dilution of the CD46 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the CD46 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    CD46

    别名

    CD46

    背景

    Recognizes a protein of 52  kDa-58  kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.

    途径

    Regulation of Actin Filament Polymerization
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