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ODC1 抗体

This anti-ODC1 antibody is a 小鼠 单克隆 antibody detecting ODC1 in WB, IF, FACS 和 IHC (p). Suitable for 人 和 大鼠.
产品编号 ABIN3025563
发货至: 中国

Quick Overview for ODC1 抗体 (ABIN3025563)

抗原

See all ODC1 抗体
ODC1 (Ornithine Decarboxylase 1 (ODC1))

适用

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人, 大鼠

宿主

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小鼠

克隆类型

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  • 43
单克隆

标记

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This ODC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

ODC1-487
  • 纯化方法

    Protein G affinity chromatography

    免疫原

    Recombinant human protein was used as the immunogen for the Ornithine Decarboxylase antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal dilution of the Ornithine Decarboxylase antibody should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Ornithine Decarboxylase antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    ODC1 (Ornithine Decarboxylase 1 (ODC1))

    别名

    Ornithine Decarboxylase

    背景

    Recognizes a 53  kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
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