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Recombinant Nkx2-2 抗体

This 兔 单克隆 antibody specifically detects Nkx2-2 in IF 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN3025346
发货至: 中国
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Quick Overview for Recombinant Nkx2-2 抗体 (ABIN3025346)

抗原

See all Nkx2-2 抗体
Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

抗体类型

Recombinant Antibody

适用

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宿主

  • 84
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克隆类型

  • 92
  • 50
单克隆

标记

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This Nkx2-2 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RMNK2-1
  • 纯化方法

    Protein A affinity chromatography

    免疫原

    A human partial recombinant protein was used as the immunogen for this rabbit monoclonal NKX2.2 antibody.

    亚型

    IgG kappa
  • 应用备注

    Titering of the NKX2.2 antibody may be required for optimal performance.

    1. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.\. IF: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the NKX2.2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

    别名

    NKX2.2

    背景

    NKX2.2 acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). [UniProt]

    基因ID

    4821

    途径

    Dopaminergic Neurogenesis
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