NGFR 抗体 (Extracellular)
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Quick Overview for NGFR 抗体 (Extracellular) (ABIN3025051)
抗原
See all NGFR 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-160, Extracellular
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原理
- NGF Receptor Antibody (azide and preservative free)
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无交叉反应
- 小鼠, 大鼠
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产品特性
- It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
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纯化方法
- Protein G affinity chromatography
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免疫原
- NGFR from A875 melanoma cells was used as the immunogen for the NGF Receptor antibody. Its epitope is within amino acids 1-160 of the extracellular domain of NGFR/NTR.
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亚型
- IgG1, kappa
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anti-Nerve Growth Factor Receptor (NGFR) (AA 301-400) antibody
NGFR 适用: 人, 大鼠, 小鼠 WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR 适用: 人 IHC 宿主: 小鼠 Monoclonal NGFR-1964 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 188-203), (Extracellular), (Stalk Region) antibodyKO Validated NGFR 适用: 人 WB, IHC, IF, FACS, IP, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal rNGFR-1965 unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, 大鼠, Non-Human Primate, 兔 WB, IHC 宿主: 兔 Monoclonal NGFR-1997R unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 2F1C2 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, Non-Human Primate, 兔, Cat, 雪貂 WB, FACS, IHC (p), IP, ICC, ICFC, MS 宿主: 小鼠 Monoclonal NGFR5 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 8G3G10 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR 适用: 人, 兔, Cat, 雪貂, 猴, Baboon IHC, IF, FACS 宿主: 小鼠 Monoclonal NGFR5 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR 适用: 人 WB, IHC 宿主: 兔 Monoclonal NGFR-2550R unconjugated Recombinant Antibody
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应用备注
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Optimal dilution of the NGF Receptor antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the NGF Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- NGFR (Nerve Growth Factor Receptor (NGFR))
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别名
- NGF Receptor
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背景
- It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
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UniProt
- P08138
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途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
抗原
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