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NGFR 抗体 (Extracellular)

The 小鼠单克隆 anti-NGFR antibody is suitable to detect NGFR in samples from 人. It has been validated for IHC (p).

IHC

1 image

产品编号 ABIN3025050

发货至: 中国

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Quick Overview for NGFR 抗体 (Extracellular) (ABIN3025050)

抗原

See all NGFR 抗体

NGFR (Nerve Growth Factor Receptor (NGFR))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This NGFR antibody is un-conjugated

应用范围

Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

SPM299

Discover our top product NGFR Primary Antibody

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AA 1-160, Extracellular

原理

NGF Receptor Antibody

无交叉反应

小鼠, 大鼠

产品特性

It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.

纯化方法

Protein G affinity chromatography

免疫原

NGFR from A875 melanoma cells was used as the immunogen for the NGF Receptor antibody. Its epitope is within amino acids 1-160 of the extracellular domain of NGFR/NTR.

亚型

IgG1, kappa
anti-Nerve Growth Factor Receptor (NGFR) (AA 301-400) antibody
NGFR 适用: 人, 大鼠, 小鼠 WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibody
NGFR 适用: 人 IHC 宿主: 小鼠 Monoclonal NGFR-1964 unconjugated

anti-Nerve Growth Factor Receptor (NGFR) (AA 188-203), (Extracellular), (Stalk Region) antibody
KO Validated NGFR 适用: 人 WB, IHC, IF, FACS, IP, IC, LCI 宿主: 兔 Polyclonal unconjugated

anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibody
NGFR 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal rNGFR-1965 unconjugated Recombinant Antibody

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 人, 大鼠, Non-Human Primate, 兔 WB, IHC 宿主: 兔 Monoclonal NGFR-1997R unconjugated Recombinant Antibody

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 2F1C2 unconjugated

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 人, Non-Human Primate, 兔, Cat, 雪貂 WB, FACS, IHC (p), IP, ICC, ICFC, MS 宿主: 小鼠 Monoclonal NGFR5 unconjugated

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 8G3G10 unconjugated

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 人, 兔, Cat, 雪貂, 猴, Baboon IHC, IF, FACS 宿主: 小鼠 Monoclonal NGFR5 unconjugated

anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibody
NGFR 适用: 人 WB, IHC 宿主: 兔 Monoclonal NGFR-2550R unconjugated Recombinant Antibody

应用备注

Optimal dilution of the NGF Receptor antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

限制

仅限研究用
状态

Liquid

浓度

0.2 mg/mL

缓冲液

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store the NGF Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
抗原

NGFR (Nerve Growth Factor Receptor (NGFR))

别名

NGF Receptor

背景

It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.

UniProt

P08138

途径

NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding