Tyrosinase-Related Protein 1 抗体
Quick Overview for Tyrosinase-Related Protein 1 抗体 (ABIN3024976)
抗原
See all Tyrosinase-Related Protein 1 (TYRP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
产品特性
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.
-
亚型
- IgG2a kappa
-
-
anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibody
TYRP1 适用: 人, 小鼠, 大鼠, 犬, 山羊, 马, 兔, 绵羊, Cow, 豚鼠, 斑马鱼 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 适用: 人 IHC, ELISA, StM, Coat 宿主: 兔 Monoclonal TYRP1-2340R unconjugated Recombinant Antibody
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 257-377) antibodyTYRP1 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal TYRP1-3280 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 198-227) antibodyTYRP1 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB19412 unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 396-445) antibodyTYRP1 适用: 人, 小鼠, 大鼠, 犬, 山羊, 马, 兔, 绵羊, 豚鼠, 斑马鱼, 猴, 小鸡, Bat IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (AA 1-537) antibodyTYRP1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 适用: 人, 小鼠 IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) antibodyTYRP1 适用: 人, 小鼠 IHC, StM 宿主: 兔 Monoclonal TYRP1-1564R unconjugated
anti-Tyrosinase-Related Protein 1 (TYRP1) (Middle Region) antibodyTYRP1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Optimal dilution of the TRP1 antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the TRP1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
-
-
- Tyrosinase-Related Protein 1 (TYRP1)
-
别名
- TRP1
-
背景
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
抗原
-
