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CD70 抗体

This anti-CD70 antibody is a 小鼠 单克隆 antibody detecting CD70 in ELISA, FACS, IP, IF, IHC (fro) 和 InhA. Suitable for 人.
产品编号 ABIN3024471
发货至: 中国

Quick Overview for CD70 抗体 (ABIN3024471)

抗原

See all CD70 抗体
CD70 (CD70 Molecule (CD70))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD70 antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Inhibition Assay (InhA)

克隆位点

BU69
  • 纯化方法

    Protein G affinity chromatography

    免疫原

    The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal dilution of the CD70 antibody should be determined by the researcher.

    1. This mAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.\. ELISA (order Ab without BSA),Functional Activity: Inhibits T cell proliferation induced by dendritic cells (Order SAF formulation) (1),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunoprecipitation: 0.5-1 μg/500 μg protein lysate,Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the CD70 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    CD70 (CD70 Molecule (CD70))

    别名

    CD70

    背景

    CD70 belongs to the tumor necrosis factor (TNF) ligand family. It is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

    途径

    Cancer Immune Checkpoints
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