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Histone H2A 抗体 (pSer139)

This anti-Histone H2A antibody is a 兔 多克隆 antibody detecting Histone H2A in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6225475
发货至: 中国

Quick Overview for Histone H2A 抗体 (pSer139) (ABIN6225475)

抗原

See all Histone H2A 抗体
Histone H2A

适用

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宿主

  • 72
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克隆类型

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多克隆

标记

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This Histone H2A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pSer139

    序列

    TQASQ

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around S139 of human Histone H2AX (NP_002096.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1mg/ml

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Xiang, Laurent, Hsu, Nachtergaele, Lu, Sheng, Xu, Chen, Ouyang, Wang, Ling, Hsu, Zou, Jambhekar, He, Shi: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).

  • 抗原

    Histone H2A

    背景

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.,H2A.X,H2A/X,H2AX,Histone H2AX,H2AFX,histone H2AX,gamma H2A.X,γH2AX,Epigenetics & Nuclear Signaling,Histones,DNA Damage & Repair,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Phosphorylation,Histone H2A

    分子量

    15 kDa

    基因ID

    3014

    UniProt

    P16104
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