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LKB1 抗体 (AA 134-433)

Name: LKB1 抗体 (AA 134-433)
Brand: antibodies-online
SKU: ABIN3022973
Availability: OutOfStock

This anti-LKB1 antibody is a 兔多克隆 antibody detecting LKB1 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 3+ publications.

Western blot analysis of extracts of various cell lines, using STK11 antibody. (LKB1 抗体 (AA 134-433))

Immunohistochemistry of paraffin-embedded human stomach using STK11 antibody at dilution of 1:200 (x400 lens) (LKB1 抗体 (AA 134-433))

IHC

Immunohistochemistry (IHC) image for anti-serine/threonine Kinase 11 (STK11) (AA 134-433) antibody (ABIN3022973) (LKB1 抗体 (AA 134-433))

IHC

Immunofluorescence analysis of MCF7 cell using STK11 antibody. (LKB1 抗体 (AA 134-433))

Immunohistochemistry of paraffin-embedded human esophageal cancer using STK11 antibody. (LKB1 抗体 (AA 134-433))

11 images

(3 references)

产品编号 ABIN3022973

发货至: 中国

Datasheet as PDF

Quick Overview for LKB1 抗体 (AA 134-433) (ABIN3022973)

抗原

See all LKB1 (STK11) 抗体

LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

适用

人

宿主

兔

克隆类型

多克隆

标记

This LKB1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

抗原表位
21

19

18

15

15

15

8

7

7

7

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 134-433

序列

CGMQEMLDSV PEKRFPVCQA HGYFCQLIDG LEYLHSQGIV HKDIKPGNLL LTTGGTLKIS DLGVAEALHP FAADDTCRTS QGSPAFQPPE IANGLDTFSG FKVDIWSAGV TLYNITTGLY PFEGDNIYKL FENIGKGSYA IPGDCGPPLS DLLKGMLEYE PAKRFSIRQI RQHSWFRKKH PPAEAPVPIP PSPDTKDRWR SMTVVPYLED LHGADEDEDL FDIEDDIIYT QDFTVPGQVP EEEASHNGQR RGLPKAVCMN GTEAAQLSTK SRAEGRAPNP ARKACSASSK IRRLSACKQQ

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 134-433 of human LKB1 (NP_000446.1).

亚型

IgG
anti-serine/threonine Kinase 11 (STK11) (AA 14-44), (N-Term) antibody
STK11 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB3547 unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 14-44) antibody
STK11 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (pSer428) antibody
STK11 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 19-48) antibody
STK11 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 1-433) antibody
STK11 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (Internal Region) antibody
STK11 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (pThr189) antibody
STK11 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (N-Term) antibody
STK11 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) antibody
STK11 适用: 人, 小鼠, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4H12 unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 393-420), (C-Term) antibody
STK11 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB37144 unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Zhang, Geng, Liu, Li, Gao, Liu, Fang, Chang: "Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1." in: Molecular metabolism, Vol. 6, Issue 1, pp. 138-147, (2018) (PubMed).

Yan, Du, Li, Chen, Yan, Chen, Hu, Chang: "CO suppresses prostate cancer cell growth by directly targeting LKB1/AMPK/mTOR pathway in vitro and in vivo." in: Urologic oncology, Vol. 36, Issue 6, pp. 312.e1-312.e8, (2018) (PubMed).

Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).
抗原

LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

别名

STK11

背景

This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.,LKB1,PJS,hLKB1,STK11,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect,Regulator of mTOR complex function,STK11

分子量

45 kDa/48 kDa

基因ID

6794

UniProt

Q15831

途径

AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect